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Search Results for " bix 02188 "

2

Compounds

Cat No. Product Name Synonyms Targets
T6324 (E/Z)-BIX02188 334949-59-6 ERK , MEK , TGF-beta/Smad
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
T1744 BIX02188 Apoptosis , MEK
BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD.
TargetMol